Pioneers in research that has led to better health and medicine world-wide, Weizmann has a long list of achievements.
Not every DNA mistake gets fixed. Researchers at the Weizmann Institute of Science have uncovered how repair enzymes choose which genetic damage deserves attention. When a wound does not heal properly, it leaves a scar. Similarly, mutations – which are permanent...
The blockbuster drug Viagra may strengthen a newly discovered cholesterol-regulating mechanism that could be harnessed to curb cancer spread, according to new collaborative research at the Weizmann Institute of Science. Viagra was originally developed to treat high...
A Phase 1 clinical trial has reported positive results for a brain-protective immunotherapy in early Alzheimer's disease, a therapy based on work from the Weizmann Institute of Science. Dozens of research teams around the world are working to halt, treat and even...
Weizmann Institute scientists have deciphered how a well-known psychedelic substance is created, and now they have engineered a plant to produce several psychedelics at once. Long before scientists began studying them in the lab, mind-altering substances were already...
Israeli and Czech scientists have recreated the coronavirus’ evolutionary journey in a test tube – revealing the conditions that can produce highly contagious variants. A key step in the origin of many pandemics occurs when an animal-borne virus infects humans and...
Weizmann Institute of Science researchers have discovered immune memory cells capable of producing antibodies against cancer – a finding that opens new avenues for future cancer vaccines. While we tend to quickly forget having been ill or having received a vaccine,...
Weizmann Institute of Science and Hebrew University of Jerusalem scientists may have solved a 150-year-old puzzle about why life favours one mirror-image molecule over another. Imagine looking at yourself in the mirror, only to find that your reflection is governed by...
Weizmann Institute of Science and Hebrew University of Jerusalem scientists have discovered that stem cell maturation can also serve as an immune defence mechanism. We all begin life as a collection of embryonic stem cells that have a remarkable ability to mature into...
An international research team led by the Weizmann Institute of Science has uncovered a key mechanism of prostate cancer treatment resistance and points to a potential combination therapy for patients. Most prostate cancers rely on male sex hormones, known as...
A new study from the Weizmann Institute of Science has revealed how energy-efficient cellular machines rapidly untangle misfolded proteins – a finding that may help improve the design of artificial molecular machines. Trying to untangle a knot in a mess of strings can...
A first-of-its-kind genetic atlas, developed by scientists at the Weizmann Institute of Science, together with colleagues at Sheba Medical Center and the Mayo Clinic, reveals how human liver cells divide their labour – and why some regions are especially vulnerable to...
A mass mating event in a Weizmann Institute of Science lab has revealed how yeast cells choose partners – and what predicts the success of their offspring. While humans often struggle to find a partner who is both physically attractive and a reliable co-parent, yeast...
Weizmann Institute of Science researchers have identified three new families of proteins that viruses use to disrupt bacterial immune signalling. The genomes of phages – viruses that infect bacteria – are largely composed of ‘dark matter’: genes that encode proteins...
The deadly malaria parasite uses its own messenger RNA to keep the host’s immune system jammed while it multiplies and spreads, researchers have discovered. RNA technology is regarded as one of the newest frontiers in medicine, but in fact a primordial innovator got...
A study conducted in Israel and Ethiopia, led by researchers at the Weizmann Institute of Science and Hadassah, reveals that the microbiome partly compensates for the immune damage caused by HIV infection. The circumstances surrounding a study on a deadly virus could...
A new Weizmann Institute of Science study has found that the genetic contribution to human lifespan is about 50 percent – more than double previous estimates. What determines how long we live – and to what extent is our lifespan shaped by our genes? Surprisingly, for...
Three resistance mutations identified in the Weizmann Institute of Science laboratory of Professor Yardena Samuels may become targets for powerful new immunotherapies. One of the most challenging moments in cancer treatment comes when a therapy stops working. In many...
Weizmann Institute of Science researchers have solved a 50-year-old mystery, uncovering the molecular mechanism that enables tissue regeneration after extensive damage. The findings may pave the way for treatments that help prevent cancer from returning. Like a...
This Weizmann Institute of Science study may shed new light on disruptions to the circadian clocks during menstruation, pregnancy and menopause. Disruptions to our circadian clocks – the internal molecular timekeepers ‘ticking’ in nearly every cell of our body...
A new tool developed by the Weizmann Institute of Science could help prepare us for the next viral threat. In 2020, as scientists around the world were racing to understand COVID-19, Professor Roy Bar-Ziv and his team at the Weizmann Institute of Science...
Weizmann Institute of Science researchers have discovered how organisms thrive at temperatures above 80 degrees Celsius. “Adapt or perish, now as ever, is nature’s inexorable imperative,” wrote H. G. Wells. This principle – that survival requires change – was mastered...
New research at the Weizmann Institute of science shows a new class of immune-activating molecules can awaken anti-tumour immunity by targeting the tumour’s own defences. Immunotherapy, which harnesses our body’s own immune system to fight cancer, has revolutionised...
Weizmann researchers, together with Beilinson and Rambam physicians, have revealed that diverse bacteria reside within brain tumours, potentially affecting treatment efficacy and even patients’ survival. Like a bouncer guarding the entrance to an exclusive nightclub,...
Weizmann Institute scientists and Ichilov physicians have used intracranial electrodes to reveal how the brain amplifies the risk of loss – and how this may help explain anxiety disorders and post-trauma effects. People are often willing to take risks to make a...