Researchers at the Weizmann Institute of Science have identified a genetic ‘switch’ that is only active when nerves are injured – recently reported in Molecular Cell. Genes that encode proteins are usually active in so many tissues and in so many different situations...
When the body needs to repair nerve injury, the machinery is already in place. Hidden within nerve cells is a ‘one-ring-to-rule-them-all’ kind of trigger: a molecular machine that can ramp up the synthesis of the necessary proteins on demand, right at the injured...
At times we all lose our nerve. But certain nerve losses, crucial during early nervous system development, may later play a role in diseases like amyotrophic lateral sclerosis (ALS) or peripheral neuropathy. New research at the Weizmann Institute of Science is...